Dr Hamish Maclachlan

Risk stratification and exercise recommendations in cardiomyopathies and channelopathies: a practical guide for the multidisciplinary team

Read the full research here Joyee Basu, Hamish MacLachlan, Raghav Bhatia, Helen Alexander, Robert Cooper, Nabeel Sheikh. Heart. Exercise offers a plethora of health benefits. However, certain genetic and acquired diseases such as cardiomyopathies and channelopathies are associated with sudden cardiac death during exercise. Several factors complicate exercise prescription in individuals living with these conditions. The lack of high-quality evidence […]

High intensity exercise programme in patients with hypertrophic cardiomyopathy: a randomised trial

Read the full research here J Basu, D Nikoletou, C Miles, H MacLachlan, G Parry-Williams, F Tilby-Jones, P Bulleros, Z Fanton, C Baker, S Purcell

High intensity exercise programme in patients with hypertrophic cardiomyopathy: a randomised trial

Read the full research here Basu, J; Nikoletou, D; Miles, C; MacLachlan, H; Parry-Williams, G; Tilby-Jones, F; Bulleros, P; Fanton, Z; Baker, C; Purcell, S; Lech, C; Chapman, T; Sage, P; Wahid, S; Sheikh, N; Jayakumar, S; Malhotra, A; Keteepe-Arachi, T; Gray, B; Finocchiaro, G; Carr-White, G; Behr, E; Tome, M; O’Driscoll, J; Chis Ster, DI; Sharma, S; Papadakis, M. European Heart Journal. Background and aims: The feasibility and impact of high intensity exercise programmes in patients with HCM is unknown. […]

Cardiac screening with ECG in the young: significance of T wave inversion, T wave depth and T wave/QRS ratio

A Alzarka, D Abioye, H Maclachlan, R Bhatia, S Sharma, M Papadakis, G Finocchiaro Read the full research here

Insights into the aetiology and temporal trends in cardiac mortality in the young: a 21-year review of national and registry data in the united kingdom

R Bhatia, T J Yeo, H Maclachlan, J Basu, N Chatrath, S Fyyaz, S Marwaha, J Westaby, E Behr, A Malhotra, G Finocchiaro, S Cox, M Sheppard, S Sharma, M Papadakis Read the full research here

Non-specific myocardial fibrosis in young competitive athletes: clinical significance and risk prediction by a powerful machine learning-based model

Read the full research here E. Androulakis, S. Marwaha, N. Dikaros, R. Bhatia, H. MacLachlan, S. Fyazz, N. Chatrath, A. Merghani, G. Finocchiaro, S. Sharma & M. Papadakis

Abstract We147: The Utility of Cardiopulmonary Exercise Testing (CPET) Amongst Male and Female athletes to Differentiate Between Physiological Left Ventricular Enlargement and Mildly Depressed Resting Systolic Function and Athletic Individuals with Dilated Cardiomyopathy.

Sarandeep Marwaha, Zephryn Fanton, Paulo Bulleros, Rachel Simmons, Raghav T Bhatia, Hamish MacLachlan, Maite Tome, Gherardo Finocchiaro, Aneil Malhotra, Sabiha Gati, Sanjay Prasad, Michael Papadakis and Sanjay Sharma Read the full research here

Mechanisms of adaptation to high intensity exercise in hypertrophic cardiomyopathy

J Basu, P Ricci, H Maclachlan, C Miles, R Bhatia, G Parry-Williams, S Sharma, M Tome, D Nikoletou, M Papadakis, J O’Driscoll. 09 November 2023. Read the paper here Abstract Background: Many individuals with hypertrophic cardiomyopathy (HCM) demonstrate exercise limitation. For a proportion this may be related to their overall cardiorespiratory fitness influenced by physical activity habits, body mechanics, or habitus. In others there is […]

Comparing clinical outcomes in bicuspid versus trileaflet aortic valve endocarditis

N Chatrath, J Dargan, R Hampal, N Kaza, R Bhatia, S Fyyaz, H Maclachlan, A Breathnatch, S Sharma, M Papadakis, M Tome Esteban, A Marciniak. 09 November 2023. Read the paper here Abstract Background: The incidence of bicuspid aortic valve infective endocarditis (BAV-IE) has been reported at 2% in contemporary BAV cohorts with an estimated risk of developing BAV-IE 11 times that of the general population […]