Dr Nikhil Chatrath

Comparing clinical outcomes in bicuspid versus trileaflet aortic valve endocarditis 

N Chatrath, J Dargan, R Hampal, N Kaza, R Bhatia, S Fyyaz, H Maclachlan, A Breathnatch, S Sharma, M Papadakis, M Tome Esteban, A Marciniak. 09 November 2023. Read the paper here Abstract Background: The incidence of bicuspid aortic valve infective endocarditis (BAV-IE) has been reported at 2% in contemporary BAV cohorts with an estimated risk of developing BAV-IE 11 times that of the general population […]

The aortic root in young adults

N Chatrath, R Bhatia, S Fyyaz, J Forster, S Marwaha, C Scrocco, N Jayaratne, B Ensam, E Androulakis, S Al-Turaihi, S Sharma, M Tome Esteban, M Papadakis. 09 November 2023. Read paper here Abstract Background: Aortic size varies between individuals and is influenced by age, gender, body size and blood pressure. There are numerous studies aimed at defining normative aortic root measurements, but the vast majority of […]

An Athlete With Bicuspid Aortic Valve Regurgitation and Left Ventricular Dilatation: A Clinical Conundrum

Nikhil Chatrath, Raghav Bhatia, Saad Fyyaz, Hamish Maclachlan, Maite Tome, Sanjay Sharma, Michael Papadakis. JACC. Case reports. 2023 May 3. Read the paper here. Abstract: The physiologic cardiac adaptations caused by intensive exercise and the pathophysiologic changes caused by significant regurgitant valvular lesions can be challenging to differentiate. We describe the clinical course of an asymptomatic 31-year-old elite triathlete with a […]

The Role of the Bicuspid Aortic Valve in Sudden Cardiac Death – Findings at Cardiac Autopsy

Nikhil Chatrath, Joseph Westaby, Gherardo Finocchiaro, Sanjay Sharma, Maite Tome Esteban, Michael Papadakis, Mary N Sheppard. Cardiovascular pathology: the official journal of the Society for Cardiovascular Pathology. 2023 Feb 22. Read the paper here Abstract: Background: Bicuspid aortic valve (BAV) is the most common congenital cardiac defect in the adult population, with a prevalence of 0.5-2%. It is well recognised that aortic […]

Physical activity and exercise recommendations for patients with valvular heart disease

Nikhil Chatrath et al. Heart (British Cardiac Society). 2022 Nov 24. Read the paper here There is a paucity of studies looking at the natural history of valvular heart disease (VHD) in exercising individuals, and exercise recommendations are largely based on expert consensus. All individuals with VHD should be encouraged to avoid sedentary behaviour by […]

An Athlete With Bicuspid Aortic Valve Regurgitation and Left Ventricular Dilatation: A Clinical Conundrum

Nikhil Chatrath, Raghav Bhatia, Saad Fyyaz, Hamish Maclachlan, Maite Tome, Sanjay Sharma, Michael Papadakis. JACC. Case reports. 2023 May 3. Read the paper here The physiologic cardiac adaptations caused by intensive exercise and the pathophysiologic changes caused by significant regurgitant valvular lesions can be challenging to differentiate. We describe the clinical course of an asymptomatic […]